SCHEMBL31389421

SCHEMBL31389421

OC1CC(c2cccnc2OC(F)(F)F)C1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 5/20 0.42
SLC6A2 P23975 5/20 0.42
SLC6A4 P31645 5/20 0.42
SLC6A3 Q01959 2/20 0.41
SSTR4 P31391 3/20 0.38
SSTR1 P30872 2/20 0.38
PDE10A Q9Y233 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31389672 0.78 HTR1A (0.38) HTR1ASLC6A2SLC6A4SLC6A3SSTR4
SCHEMBL31389417 0.76 P2RX7 (0.38) SLC6A2SLC6A4SSTR4SSTR1
SCHEMBL31389943 0.75 PROKR1 (0.39)
SCHEMBL31389655 0.71 PDK2 (0.40) SSTR4SSTR1
SCHEMBL31389511 0.71 PDK2 (0.43) SSTR4SSTR1
SCHEMBL31389895 0.70 TSHR (0.47) SLC6A4PDE10A
SCHEMBL30785493 0.70 TLR7 (0.47)
SCHEMBL18320509 0.70 TLR7 (0.47)
SCHEMBL15473322 0.67 CBFB (0.42) HTR1ASLC6A2SLC6A4SSTR4
Hydrochloric Acid SCHEMBL4005980 0.67 HTR1A (0.70) HTR1ASLC6A2SLC6A4SLC6A3PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025043225-A2 DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 GENENTECH, INC. (US) 2025-02-27 WO disclosed