Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389479 | 0.80 | EPHX1 (0.59) | EPHX1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17610028 | 0.79 | ALDH1A1 (0.59) | EPHX1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31389658 | 0.78 | L3MBTL1 (0.47) | ALDH1A1MAPTMEN1KMT2AALOX12 | |
| SCHEMBL31389407 | 0.77 | EPHX1 (0.76) | EPHX1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6118209 | 0.76 | EPHX1 (0.78) | EPHX1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3050543 | 0.75 | EPHX1 (0.69) | EPHX1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15391362 | 0.75 | MLYCD (0.57) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL21712210 | 0.75 | EPHX1 (0.61) | EPHX1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30521582 | 0.75 | EPHX1 (0.61) | EPHX1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5455469 | 0.74 | ALDH1A1 (0.80) | EPHX1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |