Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389457 | 0.83 | POLB (0.53) | CCR5MAPK1ALDH1A1TSHRMAPT | |
| SCHEMBL31389757 | 0.83 | POLB (0.34) | FPR2MAPTTP53 | |
| SCHEMBL31389529 | 0.77 | CCR5 (0.47) | FPR2CCR5MAPK1PIK3CBKDM4E | |
| SCHEMBL13543531 | 0.74 | CCR5 (0.45) | FPR2CCR5MAPK1PIK3CBKDM4E | |
| SCHEMBL3524871 | 0.74 | CCR5 (0.45) | FPR2CCR5MAPK1PIK3CBKDM4E | |
| SCHEMBL31389921 | 0.73 | — | — | |
| SCHEMBL13543532 | 0.72 | CCR5 (0.49) | FPR2CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL31389821 | 0.70 | MET (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL31389659 | 0.70 | CHRM2 (0.37) | TSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL3527138 | 0.70 | CCR5 (0.55) | FPR2CCR5CYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |