Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389471 | 0.82 | CYP11B2 (0.36) | CCR5FPR2EGFR | |
| SCHEMBL13543531 | 0.82 | CCR5 (0.45) | CCR5ALDH1A1KDM4EHPGDFPR2 | |
| SCHEMBL31389849 | 0.82 | RPS6KA5 (0.38) | CCR5FPR2CYP2D6EGFR | |
| SCHEMBL3524871 | 0.82 | CCR5 (0.45) | CCR5ALDH1A1KDM4EHPGDFPR2 | |
| SCHEMBL3527138 | 0.80 | CCR5 (0.55) | CCR5FPR2CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL31389550 | 0.79 | POLB (0.37) | CCR5MAPTTP53KMT2A | |
| SCHEMBL31389485 | 0.79 | POLB (0.58) | ALDH1A1MAPK1TSHRMAPTTP53 | |
| SCHEMBL8223841 | 0.78 | CCR5 (0.46) | CCR5ALDH1A1KDM4EHPGDFPR2 | |
| SCHEMBL31389484 | 0.77 | FPR2 (0.42) | CCR5ALDH1A1KDM4EHPGDFPR2 | |
| SCHEMBL22725453 | 0.76 | NOS2 (0.46) | CCR5ALDH1A1CYP1A2CYP2D6EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |