Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389484 | 0.83 | FPR2 (0.42) | TP53MAPTFPR2 | |
| SCHEMBL31389457 | 0.82 | POLB (0.53) | POLBHDAC1HDAC6HDAC5MET | |
| SCHEMBL31389550 | 0.78 | POLB (0.37) | POLBGRM2TP53MAPT | |
| SCHEMBL31389907 | 0.76 | ATM (0.38) | POLBHDAC1HDAC6HDAC5MET | |
| SCHEMBL31389921 | 0.71 | — | — | |
| SCHEMBL31389663 | 0.67 | SPR (0.32) | — | |
| SCHEMBL31389659 | 0.65 | CHRM2 (0.37) | MET | |
| SCHEMBL31389672 | 0.65 | HTR1A (0.38) | — | |
| SCHEMBL31390003 | 0.64 | MKNK2 (0.32) | — | |
| SCHEMBL31389817 | 0.64 | IDH1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |