Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406319 | 0.83 | APP (0.35) | TRPA1FLT3EGFRCYP2C9SMN1; SMN2 | |
| SCHEMBL20406321 | 0.80 | ALDH1A1 (0.36) | TRPA1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31395403 | 0.77 | TRPA1 (0.43) | TRPA1ALDH1A1MRGPRX1MEN1KMT2A | |
| SCHEMBL20406320 | 0.76 | EGFR (0.32) | TRPA1FLT3EGFRSMN1; SMN2KDR | |
| SCHEMBL20406318 | 0.76 | ICAM1 (0.38) | TRPA1ALDH1A1FLT3EGFRSMN1; SMN2 | |
| SCHEMBL29415410 | 0.76 | MEN1 (0.51) | TRPA1ALDH1A1MRGPRX1MEN1KMT2A | |
| SCHEMBL6611000 | 0.74 | PTGER4 (0.46) | MEN1KMT2AFLT3EGFR | |
| SCHEMBL20406662 | 0.74 | TRPA1 (0.33) | TRPA1EGFRSMN1; SMN2KDR | |
| SCHEMBL31395515 | 0.74 | PDE10A (0.53) | TRPA1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20406664 | 0.71 | CSF1R (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739307-A2 | TARGETED EPIGENETIC THERAPIES FOR DISORDERS OF PROGRANULIN DEFICIENCY | The General Hospital Corporation (US) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025010291-A2 | TARGETED EPIGENETIC THERAPIES FOR DISORDERS OF PROGRANULIN DEFICIENCY | THE GENERAL HOSPITAL CORPORATION (US) | 2025-01-09 | — | — | WO | disclosed |