Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | UBE2D3 | P61077 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 8/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22305504 | 0.77 | PTGS2 (0.40) | NLRP3UBE2D3PKM | |
| Vernoflexin SCHEMBL31570936 | 0.73 | NLRP3 (0.35) | NLRP3PKM | |
| SCHEMBL30945826 | 0.70 | NLRP3 (1.00) | NLRP3CYP2C9KCNH2 | |
| Isozaluzanin C SCHEMBL24453721 | 0.68 | PKM (0.40) | NLRP3PKM | |
| Isozaluzanin C SCHEMBL17214374 | 0.68 | PKM (0.40) | NLRP3PKM | |
| Dehydrocostuslactone SCHEMBL699070 | 0.64 | CYP19A1 (0.46) | NLRP3PKM | |
| Dehydrocostuslactone SCHEMBL936050 | 0.64 | CYP19A1 (0.46) | NLRP3PKM | |
| Dehydrocostuslactone SCHEMBL31029489 | 0.64 | CYP19A1 (0.46) | NLRP3PKM | |
| Vernoflexuoside SCHEMBL1644624 | 0.64 | PTPN1 (0.38) | — | |
| SCHEMBL22305507 | 0.61 | PKM (0.41) | NLRP3UBE2D3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462620-B | Dehydrocostuslactone derivative and preparation method and application thereof | 四川大学华西医院 | 2025-04-04 | — | — | CN | disclosed |
| CN-119462620-A | Dehydrocostuslactone derivative and preparation method and application thereof | 四川大学华西医院 | 2025-02-18 | — | — | CN | disclosed |