Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31397084 | 0.88 | HCAR3 (0.41) | MAPK1HTTRAB9ANPC1HCAR3 | |
| SCHEMBL7426294 | 0.79 | ALDH1A1 (0.46) | MAPK1HTTCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL29875081 | 0.79 | ALDH1A1 (0.46) | MAPK1HTTCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL22115089 | 0.76 | HCAR3 (0.55) | MAPK1HTTCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL27178839 | 0.75 | RAB9A (0.45) | ALDH1A1RAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL29605784 | 0.70 | ALDH1A1 (0.53) | HTTCYP4F2CYP4A11ALDH1A1RAB9A | |
| SCHEMBL27694530 | 0.70 | RAB9A (0.49) | CYP4F2CYP4A11ALDH1A1RAB9ANPC1 | |
| SCHEMBL1407913 | 0.70 | HTT (0.66) | MAPK1HTTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL521069 | 0.68 | MAPT (0.57) | HTTCYP4F2CYP4A11ALDH1A1SMN1; SMN2 | |
| SCHEMBL16412469 | 0.68 | PDGFRB (0.57) | MAPK1CYP4F2CYP4A11ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240424111-A1 | Degrader Compounds and Uses Thereof | CALICO LIFE SCIENCES LLC (US) | 2024-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240424111-A1 | Degrader Compounds and Uses Thereof | PTPN1, PTPN2, PTPN5 | MAPK1 757/4885HTT 988/4885CYP4F2 1297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.