Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL3139918

CSc1ccc([S+](c2ccccc2)c2ccccc2)cc1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.40
LMNA P02545 1/20 0.39
GPR3 P46089 2/20 0.39
KMT2A Q03164 3/20 0.37
TSHR P16473 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 2/20 0.35
PTGS2 P35354 2/20 0.35
MAPK1 P28482 1/20 0.35
GAA P10253 2/20 0.35
ESR1 P03372 1/20 0.35
HPGD P15428 1/20 0.34
TAS2R14 Q9NYV8 1/20 0.34
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL74504 0.89 ALDH1A1 (0.39) ALDH1A1LMNAGPR3KMT2ATSHR
Trifluoromethanesulfonic Acid SCHEMBL6118365 0.87 GPR3 (0.48) GPR3
SCHEMBL3144298 0.86 ALDH1A1 (0.35) ALDH1A1LMNAKMT2ATSHRSMN1; SMN2
Trifluoromethanesulfonic Acid SCHEMBL29767233 0.86 GPR3 (0.40) ALDH1A1GPR3PTGS2HPGD
Trifluoromethanesulfonic Acid SCHEMBL51462 0.86 GPR3 (0.40) ALDH1A1GPR3PTGS2HPGD
SCHEMBL3132742 0.85 ALDH1A1 (0.35) ALDH1A1LMNAKMT2ATSHRSMN1; SMN2
SCHEMBL3126430 0.85 ALDH1A1 (0.35) ALDH1A1LMNAKMT2ATSHRSMN1; SMN2
Trifluoromethanesulfonic Acid SCHEMBL37032 0.85 GPR3 (0.50) ALDH1A1GPR3TSHR
Trifluoromethanesulfonic Acid SCHEMBL31155703 0.85 GPR3 (0.50) ALDH1A1GPR3TSHR
SCHEMBL3132550 0.84 ALDH1A1 (0.39) ALDH1A1LMNAKMT2ATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-7217492-B2 Onium salt compound and radiation-sensitive resin composition JSR CORPORATION (JP) 2007-05-15 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed
US-20050053861-A1 Onium salt compound and radiation-sensitive resin composition JSR CORPORATION (JP) 2005-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 ALDH1A1 139/4885LMNA 4863/4885GPR3 973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.