SCHEMBL31402302

SCHEMBL31402302

Cc1ccc(S(=O)(=O)Nc2cccc(Cl)c2F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.59
TSHR P16473 2/20 0.59
MEN1 O00255 2/20 0.59
ALDH1A1 P00352 6/20 0.58
LMNA P02545 5/20 0.58
MAPT P10636 3/20 0.58
CYP2C9 P11712 2/20 0.58
CYP2C19 P33261 2/20 0.58
USP2 O75604 1/20 0.58
POLB P06746 1/20 0.58
NOD2 Q9HC29 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
RECQL P46063 1/20 0.54
KEAP1 Q14145 1/20 0.54
NFE2L2 Q16236 1/20 0.54
CA2 P00918 2/20 0.54
CA9 Q16790 2/20 0.54
CA1 P00915 1/20 0.54
CA4 P22748 1/20 0.54
CA7 P43166 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21497038 0.85 KMT2A (0.59) KMT2ATSHRMEN1LMNACA2
SCHEMBL2176669 0.84 LMNA (0.61) KMT2ATSHRMEN1ALDH1A1LMNA
SCHEMBL7592222 0.84 TSHR (0.71) KMT2ATSHRMEN1ALDH1A1LMNA
SCHEMBL30557370 0.84 TSHR (0.71) KMT2ATSHRMEN1ALDH1A1LMNA
SCHEMBL28605728 0.83 ALDH1A1 (0.59) KMT2ATSHRMEN1ALDH1A1LMNA
SCHEMBL21497034 0.81 CRHBP (0.58) KMT2ATSHRMEN1MAPTCA2
SCHEMBL29833597 0.79 ALDH1A1 (0.55) KMT2ATSHRMEN1ALDH1A1LMNA
SCHEMBL28728692 0.79 ALDH1A1 (0.55) KMT2ATSHRMEN1ALDH1A1LMNA
SCHEMBL12407080 0.79 LMNA (0.55) KMT2ATSHRMEN1ALDH1A1LMNA
SCHEMBL2175966 0.79 TSHR (0.72) KMT2ATSHRMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119546601-A Herbicidal benzoxazines FMC公司 2025-02-28 CN disclosed