Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31403606 | 0.95 | AURKA (0.43) | PSMD14AURKAMAPK1ATMALDH1A1 | |
| SCHEMBL31403508 | 0.92 | HPGDS (0.42) | PSMD14AURKAKDM4EALDH1A1HPGD | |
| SCHEMBL31403618 | 0.92 | HTR1A (0.43) | PSMD14AURKAMAPK1CHRNB2CHRNA7 | |
| SCHEMBL31403672 | 0.89 | DGAT1 (0.42) | PSMD14AURKAMAPK1ATMKDM4E | |
| SCHEMBL31403477 | 0.85 | GPR119 (0.45) | ALDH1A1 | |
| SCHEMBL31403604 | 0.83 | AURKA (0.48) | PSMD14AURKAMAP3K5GAAHPGD | |
| SCHEMBL31403664 | 0.82 | PIK3CA (0.40) | PSMD14EGFR | |
| SCHEMBL13199654 | 0.79 | PSMD14 (0.48) | PSMD14MAPK1ATMKDM4EALDH1A1 | |
| SCHEMBL13941183 | 0.78 | PSMD14 (0.45) | PSMD14MAPK1ATMKDM4EALDH1A1 | |
| SCHEMBL31403701 | 0.78 | AURKA (0.52) | PSMD14AURKAGAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076284-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | DELPHIA THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |