Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HTR1F | P30939 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31403604 | 0.90 | AURKA (0.48) | AURKASCDCDK4MGAMHSD17B10 | |
| SCHEMBL31403701 | 0.87 | AURKA (0.52) | AURKACDK1AURKBSCDCDK4 | |
| SCHEMBL31403618 | 0.87 | HTR1A (0.43) | KDM2BAURKAHTR1AHTR1BHTR1F | |
| SCHEMBL31403655 | 0.84 | AURKA (0.44) | AURKACDK4MGAMHSD17B10GAA | |
| SCHEMBL31403478 | 0.82 | GPR119 (0.46) | AURKBSRC | |
| SCHEMBL31403738 | 0.81 | DGAT1 (0.44) | AURKAMGAMHSD17B10GAADGAT1 | |
| SCHEMBL21671863 | 0.79 | DGAT1 (0.41) | AURKAHTR1AHTR1BHTR1FHTR1D | |
| SCHEMBL4228613 | 0.78 | HTR1A (0.53) | KDM2BHTR1AHTR1BHTR1FHTR1D | |
| SCHEMBL31403633 | 0.77 | PSMD14 (0.43) | AURKACDK4HSD17B10GAAHPGD | |
| SCHEMBL13841049 | 0.75 | HTR1A (0.61) | KDM2BHTR1AHTR1BHTR1FHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076284-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | DELPHIA THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |