Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | GJB2 | P29033 | 1/20 | 0.34 |
| ▸ | GJA1 | P17302 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782135 | 0.71 | IDO1 (0.36) | MAOBMAOANAAATRPV6IDO1 | |
| SCHEMBL8233618 | 0.70 | CTSL (0.39) | MAOBMAOANAAATRPV6IDO1 | |
| SCHEMBL3051972 | 0.70 | CTSL (0.39) | MAOBMAOANAAATRPV6IDO1 | |
| SCHEMBL8240019 | 0.70 | CTSL (0.39) | MAOBMAOANAAATRPV6IDO1 | |
| SCHEMBL3049370 | 0.68 | NAAA (0.43) | MAOBMAOANAAATRPV6IDO1 | |
| SCHEMBL9618007 | 0.68 | PKM (0.51) | MAOBTRPV6IDO1AGXTCA1 | |
| SCHEMBL28460059 | 0.68 | PKM (0.51) | MAOBTRPV6IDO1AGXTCA1 | |
| SCHEMBL9234580 | 0.68 | PKM (0.51) | MAOBTRPV6IDO1AGXTCA1 | |
| SCHEMBL26986104 | 0.66 | CA1 (0.43) | MAOBTRPV6IDO1AGXTCA1 | |
| SCHEMBL4612615 | 0.66 | CA2 (0.41) | TRPV6IDO1AGXTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119487028-A | Heterocyclic compounds, compositions thereof and methods of treatment therewith | 百济神州有限公司 | 2025-02-18 | — | — | CN | disclosed |