Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961569 | 0.81 | L3MBTL1 (0.48) | THRAL3MBTL1ATMKMT2ACYP2D6 | |
| SCHEMBL3474407 | 0.78 | L3MBTL1 (0.48) | THRAL3MBTL1ATMKMT2ACYP2D6 | |
| SCHEMBL6219063 | 0.78 | THRB (0.48) | THRAL3MBTL1ATMKMT2ACYP2D6 | |
| SCHEMBL6214353 | 0.77 | L3MBTL1 (0.47) | THRAL3MBTL1ATMKMT2ACYP2D6 | |
| SCHEMBL7850093 | 0.77 | THRA (0.43) | THRAL3MBTL1ATMKMT2ACYP2D6 | |
| SCHEMBL5846631 | 0.76 | MAPT (0.56) | THRAL3MBTL1ATMKMT2ACYP2D6 | |
| SCHEMBL10408308 | 0.76 | THRA (0.55) | THRAL3MBTL1ATMKMT2ACYP2D6 | |
| SCHEMBL31405784 | 0.75 | THRA (0.48) | THRAMAPTMAPK1ALDH1A1GAA | |
| SCHEMBL11471529 | 0.75 | THRA (0.54) | THRAL3MBTL1ATMKMT2ACYP2D6 | |
| SCHEMBL9132407 | 0.74 | L3MBTL1 (0.55) | THRAL3MBTL1ATMKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024260309-A1 | THR-β RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE METHOD THEREFOR | 西威埃医药技术（上海）有限公司 | 2024-12-26 | — | — | WO | disclosed |