Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | STAT1 | P42224 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3474407 | 0.84 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1STAT1ATMKMT2A | |
| SCHEMBL31405697 | 0.81 | THRA (0.47) | L3MBTL1ALDH1A1STAT1ATMKMT2A | |
| SCHEMBL9132407 | 0.80 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1ATMKMT2ATHRA | |
| SCHEMBL6219063 | 0.78 | THRB (0.48) | L3MBTL1ALDH1A1ATMKMT2ATHRA | |
| SCHEMBL9373746 | 0.78 | THRA (0.55) | L3MBTL1ALDH1A1ATMCA1CA2 | |
| SCHEMBL5846631 | 0.77 | MAPT (0.56) | L3MBTL1ALDH1A1ATMKMT2ATHRA | |
| SCHEMBL16703481 | 0.77 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1STAT1ATMKMT2A | |
| SCHEMBL6169134 | 0.77 | P2RX7 (0.51) | L3MBTL1STAT1ATMKMT2ATHRA | |
| SCHEMBL1412864 | 0.76 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1STAT1ATMKMT2A | |
| SCHEMBL3956559 | 0.76 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1ATMKMT2ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530129-A | Process for the preparation of 1,2,4-triazine-3,5-diones | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0695743-A1 | Process for the preparation of 1,2,4-triazine-3,5-diones | BAYER AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-4968795-A | PARASITICIDES, ANTIPROTOZOA AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |