Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 14/20 | 0.48 |
| ▸ | THRB | P10828 | 14/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29789606 | 0.80 | THRA (0.55) | THRATHRBCYP2C8CYP2C9ALDH1A1 | |
| SCHEMBL9379900 | 0.75 | THRA (0.61) | THRATHRBCYP2C8CYP2C9ALDH1A1 | |
| SCHEMBL31405697 | 0.75 | THRA (0.47) | THRATHRBALDH1A1LMNAGAA | |
| SCHEMBL5847585 | 0.75 | BCAT1 (0.56) | THRATHRBCYP2C8CYP2C9ALDH1A1 | |
| SCHEMBL10421720 | 0.75 | MEN1 (0.42) | THRATHRBCYP2C8CYP2C9 | |
| SCHEMBL10421668 | 0.75 | MEN1 (0.54) | THRATHRBCYP2C8CYP2C9ALDH1A1 | |
| SCHEMBL10420863 | 0.73 | MEN1 (0.58) | THRATHRBCYP2C8CYP2C9ALDH1A1 | |
| SCHEMBL24668703 | 0.73 | THRA (0.61) | THRATHRBCYP2C8CYP2C9ALDH1A1 | |
| SCHEMBL9134775 | 0.72 | THRA (0.56) | THRATHRBCYP2C8CYP2C9BCAT1 | |
| SCHEMBL24449337 | 0.72 | THRB (0.56) | THRATHRBCYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024260309-A1 | THR-β RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE METHOD THEREFOR | 西威埃医药技术（上海）有限公司 | 2024-12-26 | — | — | WO | disclosed |