Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2254433 | 0.72 | OPRM1 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2254436 | 0.72 | OPRM1 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6840540 | 0.71 | KCNH2 (0.46) | KCNH2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31406180 | 0.69 | ADRB1 (0.46) | KCNH2AHRGAAMAPT | |
| SCHEMBL3340549 | 0.68 | LTA4H (0.48) | LTA4HCYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL949366 | 0.68 | HTR3A (0.56) | GAAHTR7NPC1MAPTRAB9A | |
| SCHEMBL31406181 | 0.68 | CYP1A2 (0.46) | — | |
| SCHEMBL3719392 | 0.67 | HTR7 (0.47) | LTA4HCYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15515677 | 0.67 | KCNH2 (0.48) | KCNH2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3191249 | 0.67 | KMT2A (0.42) | P2RX3GAAHTR7EPHX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025014719-A2 | TROPANE COMPOUNDS FOR TREATING BRAIN DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-16 | — | — | WO | disclosed |