Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546730 | 0.92 | PARP1 (0.52) | PARP1PARP2KDM4EALOX15TSHR | |
| SCHEMBL16850278 | 0.89 | PARP1 (0.50) | PARP1PARP2KDM4EALOX15TSHR | |
| SCHEMBL31409566 | 0.86 | HDAC1 (0.49) | PARP1KDM4EALOX15TSHRSIRT1 | |
| SCHEMBL5282876 | 0.86 | HDAC1 (0.49) | PARP1KDM4EALOX15TSHRSIRT1 | |
| SCHEMBL582129 | 0.83 | ALDH1A1 (0.51) | PARP1PARP2KDM4EALOX15TSHR | |
| SCHEMBL2627975 | 0.83 | PARP1 (0.47) | PARP1PARP2KDM4EALOX15TSHR | |
| SCHEMBL29427924 | 0.82 | ALOX15 (0.65) | PARP1PARP2KDM4EALOX15TSHR | |
| SCHEMBL741365 | 0.82 | ALOX15 (0.65) | PARP1PARP2KDM4EALOX15TSHR | |
| SCHEMBL6440457 | 0.81 | ADAM17 (0.47) | PARP1PARP2KDM4EALOX15TSHR | |
| SCHEMBL16850256 | 0.80 | DAO (0.47) | PARP1PARP2KDM4EALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025006553-A1 | METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2025-01-02 | — | — | WO | disclosed |