Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 4/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | SIK1 | P57059 | 1/20 | 0.31 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.31 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31409572 | 0.92 | SCN9A (0.33) | BRD4MAPK14LCKSRCGRM2 | |
| SCHEMBL31409612 | 0.87 | NOS1 (0.31) | GRM2NOS1 | |
| SCHEMBL31409614 | 0.87 | NOS1 (0.31) | GRM2NOS1 | |
| SCHEMBL31409586 | 0.87 | NOS1 (0.31) | NOS1 | |
| SCHEMBL31409647 | 0.82 | DGAT1 (0.37) | BRD4MAPK14 | |
| SCHEMBL31409705 | 0.72 | DYRK1A (0.36) | BRD4LMNAMAPTHTT | |
| SCHEMBL14115603 | 0.70 | IGF1R (0.64) | MAOBIGF1RCAMK2DLCKSRC | |
| SCHEMBL31617596 | 0.68 | IDH1 (0.34) | BRD4KDM4EMAPTHTT | |
| SCHEMBL31617590 | 0.66 | NPBWR1 (0.33) | BRD4MAPTSMN1; SMN2 | |
| SCHEMBL31617466 | 0.66 | SCN8A (0.37) | BRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |