Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31409562 | 0.87 | BRD4 (0.35) | NOS1 | |
| SCHEMBL31409572 | 0.87 | SCN9A (0.33) | NOS1 | |
| SCHEMBL31409614 | 0.86 | NOS1 (0.31) | NOS1 | |
| SCHEMBL31409612 | 0.86 | NOS1 (0.31) | NOS1 | |
| SCHEMBL31409647 | 0.82 | DGAT1 (0.37) | — | |
| SCHEMBL31409705 | 0.69 | DYRK1A (0.36) | — | |
| SCHEMBL31617596 | 0.65 | IDH1 (0.34) | — | |
| SCHEMBL31617590 | 0.63 | NPBWR1 (0.33) | — | |
| SCHEMBL31617466 | 0.62 | SCN8A (0.37) | — | |
| SCHEMBL23791762 | 0.62 | DUT (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |