Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.36 |
| ▸ | SELE | P16581 | 2/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PRKX | P51817 | 1/20 | 0.35 |
| ▸ | NEK4 | P51957 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25355309 | 0.83 | SCN5A (0.36) | SLC6A4ICAM1SELEDYRK1ASCN9A | |
| SCHEMBL4787805 | 0.77 | ALDH1A1 (0.45) | CA1CA2CA9LTA4HKDM4E | |
| SCHEMBL3829192 | 0.76 | LTA4H (0.44) | LTA4HKDM4ELMNARAB9AL3MBTL1 | |
| SCHEMBL5942897 | 0.76 | MLYCD (0.41) | SLC6A4THRBICAM1SELELTA4H | |
| SCHEMBL28715184 | 0.74 | SLC6A4 (0.38) | SLC6A4THRBICAM1SELEDYRK3 | |
| SCHEMBL23632075 | 0.73 | THRB (0.38) | SLC6A4THRBCA1CA2CA9 | |
| SCHEMBL11148692 | 0.72 | CA1 (0.52) | CA1CA2CA9LTA4HSCN9A | |
| SCHEMBL1685383 | 0.72 | CA1 (0.52) | CA1CA2CA9LTA4HSCN9A | |
| SCHEMBL9262733 | 0.71 | SLC6A4 (0.53) | SLC6A4THRBCA1CA2CA9 | |
| SCHEMBL28715176 | 0.71 | THRB (0.34) | SLC6A4THRBCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |