Perchlorate

Perchlorate

SCHEMBL3140966

Fc1ccc([S+](c2ccccc2)c2ccc(F)cc2)cc1.[O-][Cl+3]([O-])([O-])[O-]

nearest known ligand 0.38

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
TSHR P16473 2/20 0.38
ALOX15 P16050 1/20 0.38
RECQL P46063 1/20 0.38
NFE2L2 Q16236 1/20 0.38
PTGS2 P35354 2/20 0.37
PTGS1 P23219 1/20 0.37
PKM P14618 1/20 0.33
KCNN4 O15554 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
NOX1 Q9Y5S8 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perchlorate SCHEMBL3139590 1.00 ALDH1A1 (0.38) ALDH1A1MAPTTSHRALOX15RECQL
SCHEMBL11980109 0.91 NFE2L2 (0.44) ALDH1A1MAPTTSHRALOX15RECQL
SCHEMBL686199 0.91 NFE2L2 (0.44) ALDH1A1MAPTTSHRALOX15RECQL
SCHEMBL685318 0.91 NFE2L2 (0.44) ALDH1A1MAPTTSHRALOX15RECQL
Hydrochloric Acid SCHEMBL31106430 0.88 NFE2L2 (0.42) ALDH1A1MAPTTSHRALOX15RECQL
Hydrochloric Acid SCHEMBL1003477 0.88 NFE2L2 (0.42) ALDH1A1MAPTTSHRALOX15RECQL
Bromide SCHEMBL3139897 0.88 NFE2L2 (0.42) ALDH1A1MAPTTSHRALOX15RECQL
Bromide SCHEMBL3139600 0.88 NFE2L2 (0.42) ALDH1A1MAPTTSHRALOX15RECQL
Perchlorate SCHEMBL108183 0.85 CYP3A4 (0.33) ALDH1A1TSHRPTGS2NPC1RAB9A
SCHEMBL3140033 0.84 NFE2L2 (0.39) ALDH1A1MAPTTSHRALOX15RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 ALDH1A1 139/4885MAPT 4793/4885TSHR 1087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.