Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 10/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31409661 | 0.77 | QPCT (0.41) | HDAC6DYRK1AQPCTGSK3B | |
| SCHEMBL31409641 | 0.70 | S1PR1 (0.35) | DYRK1AQPCTGSK3B | |
| SCHEMBL31409724 | 0.69 | HDAC1 (0.55) | TP53HDAC1HDAC6LMNAMAPT | |
| SCHEMBL15084530 | 0.69 | CDK5 (0.41) | DYRK1AGSK3B | |
| SCHEMBL31409637 | 0.66 | NOS1 (0.64) | TP53HDAC1HDAC6LMNAMAPT | |
| SCHEMBL6343767 | 0.65 | LMNA (0.55) | TP53LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL22502476 | 0.64 | KMO (0.34) | DYRK1AGSK3B | |
| SCHEMBL29378128 | 0.64 | KMO (0.34) | DYRK1AGSK3B | |
| SCHEMBL31409705 | 0.63 | DYRK1A (0.36) | LMNAMAPTPOLBDYRK1AGSK3B | |
| SCHEMBL27720173 | 0.63 | LMNA (0.56) | TP53LMNAMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |