SCHEMBL31410657

SCHEMBL31410657

CC(=O)C(C)(C)[C@H](N)C(=O)N[C@H](C(=O)OCc1ccccc1)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSB P07858 2/20 0.50
CTSK P43235 1/20 0.50
LNPEP Q9UIQ6 5/20 0.48
ERAP2 Q6P179 4/20 0.48
ERAP1 Q9NZ08 2/20 0.47
IL1RN P18510 1/20 0.47
ECE1 P42892 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31410669 0.82 CTSB (0.56) CTSBCTSKLNPEPERAP2ERAP1
SCHEMBL30621987 0.82 ALDH1A1 (0.54) MEN1KMT2A
Hydrochloric Acid SCHEMBL6283276 0.81 CTSB (0.55) CTSBCTSKLNPEPERAP2ERAP1
SCHEMBL23051873 0.81 CTSB (0.59) CTSBCTSKLNPEPERAP2ERAP1
SCHEMBL21274443 0.79 ERAP2 (0.56) CTSBCTSKLNPEPERAP2ERAP1
SCHEMBL21274440 0.79 ERAP2 (0.56) CTSBCTSKLNPEPERAP2ERAP1
SCHEMBL9099082 0.79 CTSK (0.51) CTSBCTSKLNPEPERAP2ERAP1
SCHEMBL9099075 0.79 CTSB (0.51) CTSBCTSKLNPEPERAP2ERAP1
Hydrochloric Acid SCHEMBL8145737 0.79 CTSB (0.55) CTSBCTSKLNPEPERAP2ERAP1
SCHEMBL29536591 0.79 CTSK (0.61) CTSBCTSKLNPEPERAP2ERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390755-A Carboline hexahydropyrazine-1, 4-diketone-3-acetyl-Val-Val, preparation and application thereof 首都医科大学 2025-02-07 CN claimed
CN-119390755-A Carboline hexahydropyrazine-1, 4-diketone-3-acetyl-Val-Val, preparation and application thereof 首都医科大学 2025-02-07 CN disclosed