Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099075 | 0.93 | CTSB (0.51) | CTSKCTSBLNPEPERAP2ERAP1 | |
| SCHEMBL29536591 | 0.87 | CTSK (0.61) | CTSKCTSBLNPEPERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL7377191 | 0.83 | CTSK (0.58) | CTSKCTSBLNPEPERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL7332600 | 0.82 | SLC15A1 (0.52) | CTSKCTSBLNPEPERAP2ERAP1 | |
| SCHEMBL31410669 | 0.80 | CTSB (0.56) | CTSKCTSBLNPEPERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL6283276 | 0.79 | CTSB (0.55) | CTSKCTSBLNPEPERAP2ERAP1 | |
| SCHEMBL29770313 | 0.79 | ERAP2 (0.68) | CTSKCTSBLNPEPERAP2ERAP1 | |
| SCHEMBL31410657 | 0.79 | CTSB (0.50) | CTSKCTSBLNPEPERAP2ERAP1 | |
| SCHEMBL23051873 | 0.79 | CTSB (0.59) | CTSKCTSBLNPEPERAP2ERAP1 | |
| SCHEMBL9098313 | 0.79 | CTSB (0.41) | CTSKCTSBLNPEPERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732399-A2 | Chymotrypsin-like proteases and their inhibitors | CEPHALON, INC. (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0518955-A4 | CHYMOTRYPSIN-LIKE PROTEASES AND THEIR INHIBITORS | — | 1993-09-22 | — | — | EP | disclosed |
| EP-0518955-A1 | CHYMOTRYPSIN-LIKE PROTEASES AND THEIR INHIBITORS | CEPHALON, INC. (US) | 1992-12-23 | — | — | EP | disclosed |
| WO-1991013904-A1 | CHYMOTRYPSIN-LIKE PROTEASES AND THEIR INHIBITORS | CEPHALON, INC. (US) | 1991-09-19 | — | — | WO | disclosed |