SCHEMBL29536591

SCHEMBL29536591

CC(C)C[C@H](N)C(=O)N[C@H](C(=O)OCc1ccccc1)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSK P43235 6/20 0.61
CTSB P07858 3/20 0.61
LNPEP Q9UIQ6 5/20 0.52
ERAP2 Q6P179 4/20 0.52
ERAP1 Q9NZ08 2/20 0.52
CTSD P07339 1/20 0.51
IL1RN P18510 1/20 0.49
CTSS P25774 2/20 0.48
CTSL P07711 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7377191 0.93 CTSK (0.58) CTSKCTSBLNPEPERAP2ERAP1
SCHEMBL29770321 0.88 CTSB (0.56) CTSKCTSBLNPEPERAP2ERAP1
SCHEMBL29832541 0.88 CTSB (0.56) CTSKCTSBLNPEPERAP2ERAP1
Hydrochloric Acid SCHEMBL7332600 0.88 SLC15A1 (0.52) CTSKCTSBLNPEPERAP2ERAP1
SCHEMBL9099075 0.87 CTSB (0.51) CTSKCTSBLNPEPERAP2ERAP1
SCHEMBL9099082 0.87 CTSK (0.51) CTSKCTSBLNPEPERAP2ERAP1
SCHEMBL14493054 0.87 CTSK (0.53) CTSKCTSBCTSSCTSL
SCHEMBL27824395 0.86 CTSK (0.58) CTSKCTSBCTSSCTSL
SCHEMBL11209394 0.86 CTSK (0.58) CTSKCTSBCTSSCTSL
SCHEMBL31410669 0.85 CTSB (0.56) CTSKCTSBLNPEPERAP2ERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112812149-B Amino acid derivative, preparation method and application thereof, anti-tumor micelle and preparation method thereof 首都医科大学 2022-04-29 CN claimed
CN-113105524-B Polypeptide derivative copper complex, preparation method and application thereof, and anticancer drug 首都医科大学 2022-05-17 CN disclosed
CN-112812149-B Amino acid derivative, preparation method and application thereof, anti-tumor micelle and preparation method thereof 首都医科大学 2022-04-29 CN disclosed
CN-112691081-B Paclitaxel micelle based on (S) -2-decanoylamino-3- (1-naphthyl) propionyl-leucyl-valine 首都医科大学 2022-04-22 CN disclosed