SCHEMBL3141139

SCHEMBL3141139

O=C(Oc1cc(F)c(F)c(F)c1F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.34
CES1 P23141 2/20 0.34
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA4 P22748 2/20 0.32
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10180644 0.85 CES2 (0.32) CES2CES1CA1CA2CA4
SCHEMBL24901032 0.84 CES2 (0.31) CES2CES1
SCHEMBL10179743 0.83 CES2 (0.42) CES2CES1CA1CA2CA4
SCHEMBL29671299 0.83 ELANE (0.44)
SCHEMBL10180776 0.81 CES2 (0.41) CES2CES1EPHX2
SCHEMBL10181509 0.80 EPHX2 (0.35) CES2CES1CA1CA2CA4
SCHEMBL474387 0.79 CES2 (0.39) CES2CES1CA1CA2CA4
SCHEMBL20156673 0.78 CES2 (0.38) CES2CES1CA1CA2CA4
SCHEMBL10181736 0.76 CES2 (0.41) CES2CES1CA1CA2CA4
SCHEMBL31006941 0.76 CYP4F2 (0.47) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7544518-B2 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON (US) 2009-06-09 US claimed
US-20050233399-A1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON 2005-10-20 US claimed
JP-3256539-B2 2002-02-12 JP claimed
EP-0547142-A4 MICROPROBE CORP (US) 1995-01-18 EP claimed
EP-0547142-A1 SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE EPOCH PHARMACEUTICALS, INC. (US) 1993-06-23 EP claimed
WO-1992003464-A1 SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE MICROPROBE CORPORATION (US) 1992-03-05 WO claimed
CN-116964076-A Compounds or salts thereof, and antibodies derived therefrom 味之素株式会社 2023-10-27 CN disclosed
CN-116829573-A Compounds or salts thereof, and antibodies derived therefrom 味之素株式会社 2023-09-29 CN disclosed
WO-2022191283-A1 COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED USING SAME 味の素株式会社 2022-09-15 WO disclosed
US-10660970-B2 Nucleic acid constructs and methods of using the same GENEVANT SCIENCES GMBH (CH) 2020-05-26 US disclosed
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed
WO-1997027331-A9 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES 1997-10-09 WO disclosed
WO-1997027331-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES RAPIGENE, INC. (US) 1997-07-31 WO disclosed
WO-1997027327-A2 METHODS AND COMPOSITIONS FOR DETECTING BINDING OF LIGAND PAIR USING NON-FLUORESCENT LABEL RAPIGENE, INC. (US) 1997-07-31 WO disclosed
WO-1997027325-A2 METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID MOLECULES UTILIZING SIZING TECHNIQUES RAPIGENE, INC. (US) 1997-07-31 WO disclosed
US-5574142-A DRUG DELIVERY TO TARGET CELLS, ANTISENSE OLIGODEOXYNUCLEOTIDES MICROPROBE CORPORATION (US) 1996-11-12 US disclosed
WO-1994013325-A9 PEPTIDE LINKERS FOR IMPROVED OLIGONUCLEOTIDE DELIVERY 1994-08-18 WO disclosed
WO-1994013325-A2 PEPTIDE LINKERS FOR IMPROVED OLIGONUCLEOTIDE DELIVERY MICROPROBE CORPORATION (US) 1994-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10660970-B2 Nucleic acid constructs and methods of using the same EXOSC5, DIS3, MTREX CES2 1937/4885CES1 2573/4885CA1 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.