Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411358 | 0.98 | HTR1A (0.47) | HTR1AHRH3SIGMAR1KCNH2KDM4E | |
| Fumaric Acid SCHEMBL31411390 | 0.91 | ACHE (0.39) | HTR1ASIGMAR1KDM4EMAPK1GFER | |
| SCHEMBL31411362 | 0.79 | HTR1A (0.36) | HTR1AHRH3DRD2 | |
| SCHEMBL31411305 | 0.77 | HTR1A (0.43) | HTR1AKDM4EHTR2AHTR2C | |
| SCHEMBL31411489 | 0.76 | HTR1A (0.42) | HTR1AHRH3SIGMAR1KCNH2KDM4E | |
| SCHEMBL31411332 | 0.74 | ALDH1A1 (0.36) | HTR1AKDM4EHTR2ADRD2HTR2C | |
| SCHEMBL31411361 | 0.74 | HTR1A (0.39) | HTR1AHRH3HTR2ACYP3A4 | |
| SCHEMBL31411340 | 0.73 | HTR1A (0.33) | HTR1AKDM4EHTR2A | |
| SCHEMBL31411448 | 0.73 | HTR1A (0.40) | HTR1AHRH3SIGMAR1KCNH2KDM4E | |
| SCHEMBL31411365 | 0.71 | HTR1A (0.41) | HTR1AHRH3SIGMAR1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735425-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2026-05-06 | — | — | EP | disclosed |
| US-20250353818-A1 | Compounds | Psylo Pty Ltd (AU) | 2025-11-20 | — | — | US | disclosed |
| US-12428380-B2 | Compounds | Psylo Pty Ltd (AU) | 2025-09-30 | — | — | US | disclosed |
| US-20250214943-A1 | Compounds | Psylo Pty Ltd (AU) | 2025-07-03 | — | — | US | disclosed |
| WO-2025000053-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2025-01-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214943-A1 | Compounds | NLN, SLC18A2, PYGB | HTR1A 185/4885HRH3 2746/4885SIGMAR1 497/4885 |
| US-12428380-B2 | Compounds | NLN, SLC18A2, PYGB | HTR1A 185/4885HRH3 2746/4885SIGMAR1 497/4885 |
| US-20250353818-A1 | Compounds | NLN, SLC18A2, PYGB | HTR1A 185/4885HRH3 2746/4885SIGMAR1 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.