SCHEMBL31411482

SCHEMBL31411482

COc1cc2cnn(S(=O)(=O)c3ccc(C)cc3)c2cc1F

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
ALDH3A1 P30838 1/20 0.43
MAPT P10636 7/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 2/20 0.42
RORC P51449 2/20 0.41
HTT P42858 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
LMNA P02545 3/20 0.38
OPRD1 P41143 2/20 0.38
SLC9A1 P19634 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
POLB P06746 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29712220 0.83 KMT2A (0.44) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL27187998 0.83 KMT2A (0.44) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL22359388 0.82 RORC (0.41) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL29804026 0.77 OPRD1 (0.48) TSHRALDH3A1MAPTMEN1KMT2A
SCHEMBL22359623 0.77 RORC (0.38) TSHRKMT2AALDH1A1RORCOPRD1
SCHEMBL31411304 0.77 MAPT (0.40) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL31411280 0.76 KMT2A (0.45) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL27187882 0.75 OPRD1 (0.40) TSHRALDH3A1MAPTMEN1KMT2A
SCHEMBL27187879 0.75 OPRD1 (0.40) TSHRALDH3A1MAPTMEN1KMT2A
SCHEMBL31411447 0.74 MAPT (0.40) TSHRALDH3A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB TSHR 1561/4885ALDH3A1 820/4885MAPT 139/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB TSHR 1561/4885ALDH3A1 820/4885MAPT 139/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB TSHR 1561/4885ALDH3A1 820/4885MAPT 139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.