SCHEMBL31411280

SCHEMBL31411280

COc1cc(F)c2c(cnn2S(=O)(=O)c2ccc(C)cc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.45
MAPT P10636 5/20 0.45
MEN1 O00255 4/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
CD4 P01730 2/20 0.42
PKM P14618 4/20 0.41
NFKBIA P25963 1/20 0.40
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
TNF P01375 1/20 0.39
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
CXCR2 P25025 1/20 0.38
AGTR1 P30556 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26551198 0.88 KMT2A (0.46) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL31411455 0.86 MAPT (0.43) KMT2AMAPTMEN1ALDH1A1PKM
SCHEMBL31411482 0.76 TSHR (0.43) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL31411447 0.74 MAPT (0.40) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL29937579 0.72 OPRD1 (0.47) KMT2AMAPTMEN1CD4
SCHEMBL29804026 0.72 OPRD1 (0.48) KMT2AMAPTMEN1ALDH1A1PKM
SCHEMBL26654876 0.72 ALDH1A1 (0.40) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL22359388 0.68 RORC (0.41) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL29712220 0.68 KMT2A (0.44) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL27187998 0.68 KMT2A (0.44) KMT2AMAPTMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB KMT2A 2336/4885MAPT 139/4885MEN1 1401/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB KMT2A 2336/4885MAPT 139/4885MEN1 1401/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB KMT2A 2336/4885MAPT 139/4885MEN1 1401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.