SCHEMBL31411447

SCHEMBL31411447

COc1ccc(F)c2c1cnn2S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.40
KMT2A Q03164 6/20 0.40
MEN1 O00255 5/20 0.40
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 2/20 0.40
LMNA P02545 3/20 0.38
HTT P42858 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALDH3A1 P30838 1/20 0.37
PKM P14618 1/20 0.36
POLB P06746 1/20 0.36
SLC9A1 P19634 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411304 0.80 MAPT (0.40) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL26551200 0.75 KMT2A (0.40) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL31411280 0.74 KMT2A (0.45) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL31411482 0.74 TSHR (0.43) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL31411468 0.74 SLC9A1 (0.42) MAPTKMT2AMEN1ALDH1A1TSHR
SCHEMBL31411455 0.71 MAPT (0.43) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL31093775 0.69 KMT2A (0.37) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL26551198 0.68 KMT2A (0.46) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL31093875 0.68 KMT2A (0.38) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL26654876 0.68 ALDH1A1 (0.40) MAPTKMT2AMEN1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB MAPT 139/4885KMT2A 2336/4885MEN1 1401/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB MAPT 139/4885KMT2A 2336/4885MEN1 1401/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB MAPT 139/4885KMT2A 2336/4885MEN1 1401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.