Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.50 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411522 | 0.81 | TP53 (0.53) | PGRPARK7ELANEMAPTTDP1 | |
| SCHEMBL9773598 | 0.80 | ELANE (0.43) | PGRELANE | |
| SCHEMBL7376832 | 0.80 | PARK7 (0.52) | PGRPARK7ELANEMAPTGSK3A | |
| SCHEMBL31411563 | 0.79 | PARK7 (0.54) | PGRPARK7ELANEMAPTMEN1 | |
| SCHEMBL9146512 | 0.76 | CASP3 (0.46) | PGRELANEBACE1MEN1KMT2A | |
| SCHEMBL31411637 | 0.75 | PGR (0.38) | PGRMAPTMEN1 | |
| SCHEMBL31411777 | 0.74 | ALDH1A1 (0.39) | PGRMAPTKDM4EMEN1KMT2A | |
| SCHEMBL31411795 | 0.74 | CRHR1 (0.39) | PGRBACE1 | |
| SCHEMBL10159046 | 0.71 | ELANE (0.62) | PARK7ELANEMAPTKDM4EGSK3A | |
| SCHEMBL9199579 | 0.70 | ELANE (0.43) | PGRELANEKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |