Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DBH | P09172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26129994 | 0.76 | CYP11B1 (0.47) | GRM2KCNH2HSP90AA1LMNAL3MBTL1 | |
| SCHEMBL31434507 | 0.74 | TRAP1 (0.43) | KCNH2HSP90AA1HSP90B1MEN1CYP1A2 | |
| SCHEMBL31412907 | 0.68 | KCNH2 (0.40) | KCNH2LMNAL3MBTL1 | |
| SCHEMBL25219157 | 0.67 | — | — | |
| SCHEMBL10577272 | 0.66 | KCNH2 (0.34) | KCNH2HSP90AA1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL10583377 | 0.66 | — | — | |
| SCHEMBL7964589 | 0.65 | LMNA (0.51) | GRM2KCNH2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL10573932 | 0.65 | DBH (0.48) | HSP90AA1HSP90B1DBH | |
| SCHEMBL31412914 | 0.65 | KCNH2 (0.47) | GRM2KCNH2LMNAL3MBTL1 | |
| SCHEMBL10578492 | 0.65 | KCNH2 (0.32) | KCNH2DBH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025044926-A1 | THIENYLSULFONYL CARBAMATES AS AT2R AGONISTS | 武汉人福创新药物研发中心有限公司 | 2025-03-06 | — | — | WO | disclosed |
| CN-119504723-A | Thiophene sulfonyl carbamates as AT2R agonists | 武汉人福创新药物研发中心有限公司 | 2025-02-25 | — | — | CN | disclosed |