SCHEMBL344711

SCHEMBL344711

O=C(O)c1c(O)c(O)c2ccccc2c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 4/20 0.50
▸ HPGD P15428 3/20 0.50
▸ KDM4E B2RXH2 3/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ CYP2C9 P11712 2/20 0.50
▸ TSHR P16473 2/20 0.50
▸ THRB P10828 1/20 0.50
▸ ALOX12 P18054 1/20 0.50
▸ ATIC P31939 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ GLA P06280 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ DHODH Q02127 3/20 0.47
▸ PDE10A Q9Y233 2/20 0.47
▸ MAPT P10636 1/20 0.47
▸ PKM P14618 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ CA12 O43570 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31414101 0.90 HSD17B10 (0.54) HSD17B10HPGDKDM4EMEN1ALDH1A1
SCHEMBL4415520 0.90 HSD17B10 (0.54) HSD17B10HPGDKDM4EMEN1ALDH1A1
SCHEMBL6450325 0.88 DHODH (0.50) HSD17B10HPGDKDM4EMEN1ALDH1A1
SCHEMBL901598 0.88 HSD17B10 (0.48) HSD17B10HPGDKDM4EMEN1ALDH1A1
SCHEMBL31039922 0.88 DHODH (0.50) HSD17B10HPGDKDM4EMEN1ALDH1A1
SCHEMBL28261469 0.86 DHODH (0.52) HSD17B10HPGDKDM4EMEN1ALDH1A1
SCHEMBL29260803 0.85 DHODH (0.55) HSD17B10HPGDKDM4EMEN1ALDH1A1
SCHEMBL27572021 0.84 HSD17B10 (0.48) HSD17B10HPGDKDM4EMEN1ALDH1A1
SCHEMBL2477681 0.83 HSD17B10 (0.58) HSD17B10HPGDKDM4EMEN1ALDH1A1
SCHEMBL19203141 0.83 LDHA (0.49) HSD17B10HPGDKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3164196-B1 TOPICAL FORMULATIONS FOR UV PROTECTION TOPGENIX INC (US) 2021-08-18 — — EP claimed
EP-3164196-A1 TOPICAL FORMULATIONS FOR UV PROTECTION TOPGENIX, INC. (US) 2017-05-10 — — EP claimed
WO-2015195546-A1 TOPICAL FORMULATIONS FOR UV PROTECTION TopGeniX, Inc. (US) 2015-12-23 — — WO claimed
US-20230296984-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-09-21 — — US disclosed
US-20230296984-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-09-21 — — US disclosed
US-20210397090-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION AND METHOD FOR FORMING RESIST PATTERN USING THE SAME NISSAN CHEMICAL CORPORATION (JP) 2021-12-23 — — US disclosed
EP-3164196-B1 TOPICAL FORMULATIONS FOR UV PROTECTION TOPGENIX INC (US) 2021-08-18 — — EP disclosed
US-20190224105-A9 COMPOUND, COMPOSITION, AND METHOD FOR PROTECTING SKIN FROM HIGH ENERGY VISIBLE LIGHT PHOTOPROTECTIVE TECHNOLOGIES, INC. (US) 2019-07-25 — — US disclosed
US-10357124-B2 Compound, composition, and method for protecting skin from high energy visible light PHOTOPROTECTIVE TECH INC (US) 2019-07-23 — — US disclosed
US-20190008306-A1 COMPOUND, COMPOSITION, AND METHOD FOR PROTECTING SKIN FROM HIGH ENERGY VISIBLE LIGHT PHOTOPROTECTIVE TECH INC (US) 2019-01-10 — — US disclosed
EP-2405885-B1 THICKENING ADDITIVE COMPOSITIONS FOR SUNSCREEN FORMULATIONS ISP INVESTMENTS LLC (US) 2018-10-24 — — EP disclosed
EP-0412706-B1 Vehicle systems for use in cosmetic compostions PROCTER & GAMBLE (US) 1995-09-27 — — EP disclosed
EP-0412710-B1 Vehicle systems for use in cosmetic compositions PROCTER & GAMBLE (US) 1995-07-19 — — EP disclosed
US-5277899-A Quaternary ammonium surfactant THE PROCTER & GAMBLE COMPANY (US) 1994-01-11 — — US disclosed
US-5106609-A Hydrophobically modified nonionic water soluble polymer, water insoluble surfactant, compatible solvent THE PROCTER & GAMBLE COMPANY (US) 1992-04-21 — — US disclosed
US-5104646-A Hydrophobically modified nonionic water soluble polymer, water soluble surfactant, compatible solvent THE PROCTER & GAMBLE COMPANY (US) 1992-04-14 — — US disclosed
US-5100658-A Hair treating compositions, hydrophobically modified cellulose ether, water soluble thickener, polysiloxane graft polymer THE PROCTER & GAMBLE COMPANY (US) 1992-03-31 — — US disclosed
EP-0412706-A2 Vehicle systems for use in cosmetic compostions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 — — EP disclosed
EP-0412710-A2 Vehicle systems for use in cosmetic compositions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 — — EP disclosed
EP-0412705-A2 Vehicle systems for use in cosmetic compositions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190224105-A9 COMPOUND, COMPOSITION, AND METHOD FOR PROTECTING SKIN FROM HIGH ENERGY VISIBLE LIGHT CUTA, TYR, XPA HSD17B10 984/4885HPGD 72/4885KDM4E 2804/4885
US-10357124-B2 Compound, composition, and method for protecting skin from high energy visible light CUTA, TYR, XPA HSD17B10 984/4885HPGD 72/4885KDM4E 2804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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