Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PTPRC | P08575 | 3/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP4 | P49662 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14401081 | 0.80 | TDP1 (0.50) | MAPTCASP1CASP3CASP4CASP7 | |
| SCHEMBL16442404 | 0.77 | HTT (0.51) | MAPTALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL7741732 | 0.77 | PTPRC (0.63) | MAPTPTPRCS100A4CASP1CASP3 | |
| SCHEMBL26192840 | 0.77 | S100A4 (0.41) | MAPTS100A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7895458 | 0.76 | MAPT (0.45) | MAPTPTPRCS100A4CASP1CASP3 | |
| SCHEMBL4629018 | 0.74 | KEAP1 (0.55) | MAPTCASP3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30177024 | 0.74 | PIK3CD (0.42) | MAPTALDH1A1LMNASMN1; SMN2CHEK1 | |
| SCHEMBL28983677 | 0.74 | PIK3CD (0.42) | MAPTALDH1A1LMNASMN1; SMN2CHEK1 | |
| SCHEMBL31415382 | 0.73 | KEAP1 (0.53) | MAPTALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL4458062 | 0.73 | CASP3 (0.53) | MAPTCASP3ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054368-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |