Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 4/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27961329 | 0.93 | TAAR1 (0.50) | TAAR1TDP1MAOBIDO1AOC3 | |
| SCHEMBL7459305 | 0.93 | MAOB (0.59) | TAAR1TDP1MAOBIDO1AOC3 | |
| SCHEMBL1396008 | 0.89 | CA2 (0.48) | TAAR1TDP1MAOBIDO1AOC3 | |
| SCHEMBL9293968 | 0.87 | MAOB (0.48) | TAAR1TDP1MAOBIGF1RALOX15 | |
| SCHEMBL2281085 | 0.85 | TDP1 (0.71) | TAAR1TDP1MAOBHTR3ACYP2A6 | |
| SCHEMBL81407 | 0.84 | TAAR1 (0.52) | TAAR1MAOBIDO1AOC3HTR3E | |
| SCHEMBL1008937 | 0.82 | IGF1R (0.53) | TAAR1MAOBIDO1AOC3HTR3E | |
| SCHEMBL2135113 | 0.82 | TAAR1 (0.68) | TAAR1MAOBIDO1AOC3HTR3E | |
| SCHEMBL30932186 | 0.82 | TDP1 (0.67) | TAAR1TDP1MAOBCYP2A6MEN1 | |
| SCHEMBL7614753 | 0.80 | KCNH2 (0.53) | TAAR1MAOBIDO1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 566 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756843-A | Preparation method of alkyl germanium based on olefin difunctional | 南京信息工程大学 | 2024-03-26 | — | — | CN | claimed |
| CN-112358406-A | Preparation method of lorcaserin intermediate | 山东省药学科学院 | 2021-02-12 | — | — | CN | claimed |
| CN-110343197-B | Preparation method and antibacterial application of polymer type quaternary ammonium salt photocatalyst | 浙江大学 | 2020-11-06 | — | — | CN | claimed |
| CN-110343197-A | A kind of preparation method and its antibacterial application of polymeric quaternary ammonium salt photochemical catalyst | 浙江大学 | 2019-10-18 | — | — | CN | claimed |
| EP-2999692-A1 | NOVEL SYNTHETIC PROCESSES TO 8-CHLORO-3-BENZO[D]AZEPINE VIA FRIEDEL-CRAFTS ALKYLATION OF OLEFIN | LEK Pharmaceuticals d.d. (SI) | 2016-03-30 | — | — | EP | claimed |
| CN-105295274-A | Bromine-series composite flame retardant and preparation method thereof | NINGXIA RUNLONG NEW PACKAGING MATERIAL CO LTD | 2016-02-03 | — | — | CN | claimed |
| CN-104478670-A | Preparation method of 5-bromine-2-chlorine-4'-ethyoxyl diphenylmethane | UNIV CHINA PHARMA | 2015-04-01 | — | — | CN | claimed |
| US-8822727-B2 | Processes for the preparation of intermediates related to the 5-HT2C agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine | ARENA PHARMACEUTICALS, INC. (US) | 2014-09-02 | — | — | US | claimed |
| EP-2518053-A1 | PROCESS FOR THE PREPARATION OF 8-CHLORO-1-METHYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE | Arena Pharmaceuticals, Inc. (US) | 2012-10-31 | — | — | EP | claimed |
| US-8168782-B2 | synthesis of lorcaserin | ARENA PHARMACEUTICALS, INC. (US) | 2012-05-01 | — | — | US | claimed |
| JP-2008516973-A | — | — | 2008-05-22 | — | — | JP | claimed |
| WO-2007120517-A2 | PROCESSES FOR THE PREPARATION OF 8-CHLORO-1-METHYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE AND INTERMEDIATES RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-10-25 | — | — | WO | claimed |
| EP-1446413-A4 | SYNTHESIS OF 2-ARALKOXY ADENOSINES AND 2-ALKOXYADENOSINES | KING PHARMACEUTICALS RES & DEV (US) | 2007-10-17 | — | — | EP | claimed |
| EP-1812439-A2 | KINASE INHIBITORS | Takeda San Diego, Inc. (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006044687-A2 | KINASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-04-27 | — | — | WO | claimed |
| US-6951932-B2 | Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines | KING PHARMACEUTICALS RESEARCH & DEVELOPMENT, INC. (US) | 2005-10-04 | — | — | US | claimed |
| CN-1608076-A | Synthesis of 2-aralkyloxyadenosine and 2-alkoxyadenosine | KING PHARMACEUTICALS RES & DEV (US) | 2005-04-20 | — | — | CN | claimed |
| EP-1446413-A1 | SYNTHESIS OF 2-ARALKOXY ADENOSINES AND 2-ALKOXYADENOSINES | King Pharmaceuticals Research and Development Inc. (US) | 2004-08-18 | — | — | EP | claimed |
| US-20030199686-A1 | Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. | 2003-10-23 | — | — | US | claimed |
| WO-2003035662-A1 | SYNTHESIS OF 2-ARALKOXY ADENOSINES AND 2-ALKOXYADENOSINES | KING PHARMACEUTICALS RESEARCH & DEVELOPMENT, INC. (US) | 2003-05-01 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199686-A1 | Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines | AMPD2, ADAR, ADA | TAAR1 3997/4885TDP1 1617/4885MAOB 1646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.