Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31416707 | 0.79 | ALDH1A1 (0.40) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL31361282 | 0.79 | LTA4H (0.38) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL31416817 | 0.76 | NOS3 (0.38) | — | |
| SCHEMBL18202729 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL18291540 | 0.72 | CXCR4 (0.46) | — | |
| SCHEMBL31416778 | 0.71 | FUCA1 (0.31) | — | |
| SCHEMBL20332369 | 0.70 | MAP4K4 (0.38) | — | |
| SCHEMBL31416731 | 0.69 | TLR8 (0.38) | — | |
| SCHEMBL20886081 | 0.66 | — | — | |
| SCHEMBL16973831 | 0.66 | CD274 (0.46) | CD274PDCD1LG2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2026046976-A1 | PYRAZOLOPYRIDINE PHOSPHATE ESTERS FOR MODULATING SALT-INDUCIBLE KINASE (SIK) | F. HOFFMANN-LA ROCHE AG (CH) | 2026-03-05 | — | — | WO | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |