SCHEMBL314175

SCHEMBL314175

C=CCSc1ccc(O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.44
CA2 P00918 2/20 0.44
CYP3A4 P08684 2/20 0.37
ALOX15 P16050 2/20 0.37
HIF1A Q16665 2/20 0.37
HSD17B10 Q99714 2/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 2/20 0.36
LMNA P02545 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
CA12 O43570 1/20 0.36
GMNN O75496 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CA1 P00915 1/20 0.36
CA3 P07451 1/20 0.36
MAPT P10636 1/20 0.36
TYR P14679 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8755108 0.88 L3MBTL1 (0.41) CYP3A4ALOX15MEN1KMT2AKDM4E
SCHEMBL7154447 0.83 L3MBTL1 (0.38) CYP3A4ALOX15HSD17B10MEN1KMT2A
SCHEMBL10528716 0.81 L3MBTL1 (0.46) CYP3A4ALOX15HSD17B10MEN1LMNA
SCHEMBL12218740 0.81 L3MBTL1 (0.37) NR1H2CYP3A4ALOX15TSHRMEN1
SCHEMBL6697882 0.79 L3MBTL1 (0.36) CYP3A4ALOX15MEN1KMT2AALDH1A1
SCHEMBL8521148 0.78 DAO (0.39) CA2TSHRTDP1MEN1KMT2A
SCHEMBL8746031 0.77 CA2 (0.48) NR1H2CA2CYP3A4ALOX15HIF1A
SCHEMBL8161044 0.77 SMN1; SMN2 (0.44) TSHRMEN1KMT2ANPC1ALDH1A1
SCHEMBL10516600 0.77 NPC1 (0.41) CYP3A4HSD17B10TDP1MEN1KMT2A
SCHEMBL21572118 0.77 APP (0.39) CYP3A4ALOX15MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102827668-B Synthesis method of high-base-number basic zinc carbonate lubricant additive UNIV HENAN 2013-10-16 CN claimed
CN-102827668-A Synthesis method of high-base-number basic zinc carbonate lubricant additive UNIV HENAN 2012-12-19 CN claimed
WO-2001062720-A1 METHOD FOR PRODUCING 1-CHLORO-4-[4-(ALKYLTHIO)PHENOXY]-BENZENES BAYER AKTIENGESELLSCHAFT (DE) 2001-08-30 WO claimed
EP-0156352-B1 PREPARATION OF (ALKYLTHIO-,CYCLOALKYTHIO- OR ARYLTHIO)-PHENOLS ETHYL CORPORATION (US) 1988-08-03 EP claimed
US-4547593-A REDISTRIBUTION OF HYDROCARBYLTHIO GROUPS; ALUMINUM PHENOXIDE CATALYST ETHYL CORPORATION (US) 1985-10-15 US claimed
EP-0156352-A2 Preparation of (alkylthio-,cycloalkythio- or arylthio)-phenols ETHYL CORPORATION (US) 1985-10-02 EP claimed
JP-5194374-A None JP disclosed
JP-4360864-A None JP disclosed
JP-1149762-A None JP disclosed
CN-106536500-B Selective matrix metalloproteinase inhibitors 圣母大学 2020-01-10 CN disclosed
CN-110312782-A Speed reducer lubricant compositions and speed reducer 协同油脂株式会社 2019-10-08 CN disclosed
US-10357546-B2 Acceleration of diabetic wound healing UNIVERSITY OF NOTRE DAME DU LAC (US) 2019-07-23 US disclosed
US-10357546-B2 Acceleration of diabetic wound healing UNIVERSITY OF NOTRE DAME DU LAC (US) 2019-07-23 US disclosed
US-4308199-A ANTIOXIDANTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-12-29 US disclosed
US-4143076-A MERCAPTO PHENOLIC AND ALKYLTHIO PHENOLIC ANTIOXIDANTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-03-06 US disclosed
US-4128530-A Mercapto phenolic and alkylthio phenolic antioxidants THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-12-05 US disclosed
US-4042705-A 1-Methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles and process for their manufacture HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed
US-3959487-A Control of mites with polychloro parathio phenols PPG INDUSTRIES, INC. (US) 1976-05-25 US disclosed
US-3850609-A POLYCHLORO PARATHIO PHENOLS AMERICAN CYANAMID COMPANY, A MAINE CORP. 1974-11-26 US disclosed
US-3723538-A POLYCHLORO PARATHIO PHENOLS AMERICAN CYANAMID COMPANY, A MAINE CORP. 1973-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10357546-B2 Acceleration of diabetic wound healing MMP8, MMP9, MMP1 NR1H2 3416/4885CA2 793/4885CYP3A4 3364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.