SCHEMBL314188

SCHEMBL314188

Sc1cccc2c(S)cccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 4/20 0.41
COPS5 Q92905 4/20 0.41
CYP1A2 P05177 8/20 0.37
CYP2A6 P11509 6/20 0.37
ALDH1A1 P00352 6/20 0.37
HSD17B10 Q99714 5/20 0.37
HPGD P15428 4/20 0.37
TSHR P16473 4/20 0.37
TDP1 Q9NUW8 3/20 0.37
CYP3A4 P08684 2/20 0.37
MAPT P10636 2/20 0.33
HDAC8 Q9BY41 1/20 0.33
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
THRB P10828 2/20 0.32
APP P05067 1/20 0.30
ALOX15 P16050 1/20 0.30
CASP1 P29466 1/20 0.30
SNCA P37840 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29450018 1.00 PSMD14 (0.41) PSMD14COPS5CYP1A2CYP2A6ALDH1A1
SCHEMBL29649174 0.85 CYP2A6 (0.39) PSMD14COPS5CYP1A2CYP2A6ALDH1A1
SCHEMBL331123 0.85 CYP2A6 (0.39) PSMD14COPS5CYP1A2CYP2A6ALDH1A1
SCHEMBL31157812 0.83 ALDH1A1 (0.68) ALDH1A1HSD17B10HPGDTSHRTDP1
SCHEMBL15352423 0.83 CES2 (0.33) PSMD14COPS5
SCHEMBL1402412 0.83 CYP1A2 (0.68) PSMD14COPS5CYP1A2CYP2A6ALDH1A1
SCHEMBL688017 0.83 ALDH1A1 (0.68) ALDH1A1HSD17B10HPGDTSHRTDP1
SCHEMBL10166787 0.83 IDO1 (0.52) CYP1A2ALDH1A1HSD17B10HPGDTSHR
SCHEMBL3440573 0.83 PARP1 (0.43) PSMD14COPS5ALDH1A1
SCHEMBL2760422 0.83 CYP1A2 (0.68) PSMD14COPS5CYP1A2CYP2A6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12275813-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2025-04-15 US claimed
US-20250033015-A1 POLYDISULFIDE CORE-SHELL MICROCAPSULES FIRMENICH SA (CH) 2025-01-30 US claimed
US-20250011476-A1 ARTICLES COMPRISING CROSSLINKED POLYMER NETWORK COMPRISING THIOETHER CROSSLINKS AND PROCESS OF MAKING AND USING SAME US GOV AIR FORCE (US) 2025-01-09 US claimed
US-20240368505-A1 FLUORINE-FREE CLEANING AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF Tan Kah Kee Innovation Laboratory (CN) 2024-11-07 US claimed
US-12116425-B2 Articles comprising crosslinked polymer network comprising thioether crosslinks and process of making and using same UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2024-10-15 US claimed
EP-3859804-B1 SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS CANON KK (JP) 2024-08-07 EP claimed
US-20240101724-A1 ARTICLES COMPRISING CROSSLINKED POLYMER NETWORK COMPRISING THIOETHER CROSSLINKS AND PROCESS OF MAKING AND USING SAME THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2024-03-28 US claimed
US-11879023-B2 Articles comprising crosslinked polymer network comprising thioether crosslinks and process of making and using same UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2024-01-23 US claimed
WO-2023133876-A1 FLUORINE-FREE CLEANING AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF 嘉庚创新实验室 2023-07-20 WO claimed
CN-115524371-A Application of covalent organic-inorganic hybrid superlattice material as chemical resistance type gas sensitive material 闽都创新实验室 2022-12-27 CN claimed
CN-101600737-B Method for producing modified conjugated diene polymer, and rubber composition BRIDGESTONE CORP 2015-05-13 CN claimed
EP-2676639-A1 STENT DELIVERY SYSTEM Terumo Kabushiki Kaisha (JP) 2013-12-25 EP claimed
US-20130304183-A1 STENT DELIVERY SYSTEM TERUMO KABUSHIKI KAISHA (JP) 2013-11-14 US claimed
CN-102015837-B Sulfur modified silanes for the elaboration of high refractive index materials ESSILOR INT 2012-12-05 CN claimed
EP-2276793-B1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INT (FR) 2012-08-01 EP claimed
US-8063237-B2 Sulfur modified silanes for the elaboration of high refractive index materials ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2011-11-22 US claimed
CN-102015837-A Sulfur modified silanes for the elaboration of high refractive index materials ESSILOR INT 2011-04-13 CN claimed
US-20110077341-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2011-03-31 US claimed
US-7867577-B2 hydrolyzed, concentrated, and heated polysulfides, alkenyl silanes such as vinyltrimethoxysilane; for formation of lenses ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2011-01-11 US claimed
US-20090287015-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2009-11-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110077341-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS TST, LAGE3, PSME1 PSMD14 304/4885COPS5 1652/4885CYP1A2 2447/4885
US-20090287015-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS LAGE3, TST, PSME1 PSMD14 322/4885COPS5 1587/4885CYP1A2 2254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.