Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 2/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26685887 | 1.00 | F11 (0.46) | F11JAK2DYRK1AMAPK1GSK3B | |
| SCHEMBL26685865 | 0.83 | ULK1 (0.61) | F11JAK2GSK3BULK1 | |
| SCHEMBL31240358 | 0.83 | ULK1 (0.61) | F11JAK2GSK3BULK1 | |
| SCHEMBL26686055 | 0.83 | DYRK1A (0.52) | DYRK1AMAPK1MAP4K4WNT1 | |
| SCHEMBL30633289 | 0.83 | DYRK1A (0.52) | DYRK1AMAPK1MAP4K4WNT1 | |
| SCHEMBL31420125 | 0.82 | DYRK1A (0.51) | JAK2DYRK1AMAPK1MAP4K4WNT1 | |
| SCHEMBL26685950 | 0.82 | DYRK1A (0.51) | JAK2DYRK1AMAPK1MAP4K4WNT1 | |
| SCHEMBL26686340 | 0.79 | JAK2 (0.56) | F11JAK2DYRK1AMAPK1ULK1 | |
| SCHEMBL26686403 | 0.79 | JAK2 (0.52) | JAK2DYRK1AMAPK14WNT1 | |
| SCHEMBL31240493 | 0.78 | WNT3A (0.57) | F11JAK2DYRK1AGSK3BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | claimed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |