Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31421340 | 0.89 | ALDH1A1 (0.38) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| SCHEMBL31420946 | 0.86 | GHSR (0.31) | LMNAALDH1A1TP53THRBAXL | |
| SCHEMBL31420720 | 0.86 | LMNA (0.44) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| SCHEMBL31421159 | 0.85 | ALDH1A1 (0.38) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| SCHEMBL31420569 | 0.84 | LMNA (0.42) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| SCHEMBL31421075 | 0.84 | HPGDS (0.37) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| SCHEMBL31421302 | 0.84 | ALDH1A1 (0.40) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| SCHEMBL31421133 | 0.83 | ALDH1A1 (0.40) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| SCHEMBL31420805 | 0.83 | ALDH1A1 (0.41) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| SCHEMBL31420654 | 0.83 | LMNA (0.39) | LMNAALDH1A1TP53SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-04-24 | — | — | US | disclosed |
| WO-2025064718-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | MYC, KRAS, NRAS | LMNA 3037/4885ALDH1A1 2630/4885TP53 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.