Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 11/20 | 0.51 |
| ▸ | TNKS | O95271 | 10/20 | 0.51 |
| ▸ | WNT3A | P56704 | 6/20 | 0.51 |
| ▸ | PARP1 | P09874 | 6/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 6/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.42 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.42 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586816 | 0.75 | COMT (0.68) | COMTTNKS2TNKSWNT3APARP1 | |
| SCHEMBL6631782 | 0.75 | PIN1 (0.67) | COMTTNKS2TNKSWNT3APARP1 | |
| SCHEMBL28158003 | 0.73 | PIN1 (0.71) | TNKS2TNKSWNT3APARP1PARP2 | |
| SCHEMBL25259225 | 0.71 | PDE2A (0.44) | COMTTNKS2TNKSWNT3APARP1 | |
| SCHEMBL7992002 | 0.71 | MAPK13 (0.60) | TNKS2TNKSWNT3APARP1RNASEH1 | |
| SCHEMBL6366542 | 0.70 | MAPK13 (0.59) | TNKS2TNKSWNT3APARP1RNASEH1 | |
| SCHEMBL7995288 | 0.70 | MAPK13 (0.52) | TNKS2TNKSWNT3APARP1 | |
| SCHEMBL2433653 | 0.70 | COMT (1.00) | COMTTNKS2TNKSWNT3APARP1 | |
| SCHEMBL7995390 | 0.70 | MAPK14 (0.48) | TNKS2TNKSWNT3APARP1 | |
| SCHEMBL7988191 | 0.70 | NPBWR1 (0.53) | TNKS2TNKSWNT3APARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |