Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 2/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992002 | 0.89 | MAPK13 (0.60) | NPBWR1PIN1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6366542 | 0.88 | MAPK13 (0.59) | NPBWR1PIN1KDM4EALDH1A1GLA | |
| SCHEMBL7995288 | 0.88 | MAPK13 (0.52) | PIN1KDM4EALDH1A1HPGDMAPK14 | |
| SCHEMBL7977996 | 0.87 | TRPV1 (0.49) | PIN1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7995390 | 0.87 | MAPK14 (0.48) | PIN1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7977738 | 0.85 | MAPK14 (0.56) | PIN1KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL7992039 | 0.85 | MAPK14 (0.56) | PIN1KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL7978027 | 0.85 | KDM4E (0.67) | PIN1KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL7988569 | 0.84 | ALOX5 (0.48) | NPBWR1KDM4EMEN1KMT2APARP1 | |
| SCHEMBL28158003 | 0.83 | PIN1 (0.71) | NPBWR1PIN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |