Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.34 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.33 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423292 | 0.87 | CAMKK1 (0.36) | MGLLDDB1CRBNPARP1KEAP1 | |
| SCHEMBL31422972 | 0.78 | CAMKK2 (0.43) | CAMKK1CAMKK2DHODH | |
| SCHEMBL31423010 | 0.78 | CAMKK2 (0.43) | CAMKK1CAMKK2DHODH | |
| SCHEMBL31422800 | 0.77 | CNR2 (0.36) | CAMKK1CAMKK2 | |
| SCHEMBL31422933 | 0.77 | KDM4E (0.47) | — | |
| SCHEMBL31423108 | 0.77 | SMYD3 (0.42) | CAMKK1CAMKK2 | |
| SCHEMBL31423039 | 0.74 | CAMKK2 (0.44) | CAMKK1CAMKK2DHODH | |
| SCHEMBL31423247 | 0.73 | CNR2 (0.40) | CAMKK1CAMKK2 | |
| SCHEMBL31423082 | 0.72 | PIK3CA (0.46) | PIK3CAMIFPARP1KEAP1NFE2L2 | |
| SCHEMBL31423086 | 0.72 | CNR2 (0.39) | CAMKK1CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |