Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.35 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | DDO | Q99489 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423086 | 0.88 | CNR2 (0.39) | CNR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31423163 | 0.83 | NOTUM (0.43) | CNR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31422779 | 0.80 | CNR2 (0.42) | CNR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31423273 | 0.80 | CNR2 (0.43) | CNR2KDM4EALDH1A1GAAPOLB | |
| SCHEMBL31422872 | 0.79 | CNR2 (0.46) | CNR2KDM5AKDM5BALOX5APFEN1 | |
| SCHEMBL31423057 | 0.78 | SERPINE1 (0.38) | KDM4EALDH1A1HPGDGAACAMKK2 | |
| SCHEMBL31422800 | 0.78 | CNR2 (0.36) | CNR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31423108 | 0.77 | SMYD3 (0.42) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL4551367 | 0.77 | CNR2 (0.46) | CNR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31422970 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |