Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422904 | 0.80 | MEN1 (0.35) | CNR2 | |
| SCHEMBL31423292 | 0.79 | CAMKK1 (0.36) | HCAR2CAMKK2ALDH1A1CAMKK1 | |
| SCHEMBL31423247 | 0.78 | CNR2 (0.40) | CNR2KDM5AKDM5BHCAR2CAMKK2 | |
| SCHEMBL31423070 | 0.77 | PIK3CA (0.37) | CAMKK2CAMKK1 | |
| SCHEMBL31423010 | 0.77 | CAMKK2 (0.43) | CAMKK2KDM4EPOLBCAMKK1 | |
| SCHEMBL31422972 | 0.77 | CAMKK2 (0.43) | CAMKK2KDM4EPOLBCAMKK1 | |
| SCHEMBL31423086 | 0.77 | CNR2 (0.39) | CNR2KDM5AKDM5BCAMKK2KDM4E | |
| SCHEMBL31422933 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1HPGD | |
| SCHEMBL31423108 | 0.76 | SMYD3 (0.42) | CAMKK2KDM4EALDH1A1POLBGAA | |
| SCHEMBL31422779 | 0.74 | CNR2 (0.42) | CNR2CAMKK2KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |