Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422933 | 0.82 | KDM4E (0.47) | KDRCHEK1KDM4EALDH1A1MEN1 | |
| SCHEMBL31423195 | 0.80 | MAOB (0.43) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL31423010 | 0.78 | CAMKK2 (0.43) | KDM4EPOLBCAMKK1CAMKK2MAPT | |
| SCHEMBL31422972 | 0.78 | CAMKK2 (0.43) | KDM4EPOLBCAMKK1CAMKK2MAPT | |
| SCHEMBL31423247 | 0.77 | CNR2 (0.40) | KDM4EALDH1A1POLBGAAHSD17B10 | |
| SCHEMBL31423086 | 0.76 | CNR2 (0.39) | KDM4EALDH1A1POLBGAAHSD17B10 | |
| SCHEMBL31423039 | 0.76 | CAMKK2 (0.44) | KDM4ECAMKK1CAMKK2 | |
| SCHEMBL31423292 | 0.76 | CAMKK1 (0.36) | ALDH1A1CAMKK1CAMKK2CYP2C9 | |
| SCHEMBL31422800 | 0.76 | CNR2 (0.36) | KDM4EALDH1A1POLBGAAHSD17B10 | |
| SCHEMBL31422779 | 0.75 | CNR2 (0.42) | KDM4EALDH1A1POLBGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |