Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423210 | 0.83 | CNR2 (0.44) | CNR2NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL31423247 | 0.80 | CNR2 (0.40) | CNR2POLBKDM4EALDH1A1GAA | |
| SCHEMBL31423086 | 0.79 | CNR2 (0.39) | CNR2POLBKDM4EALDH1A1GAA | |
| SCHEMBL31423057 | 0.76 | SERPINE1 (0.38) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL31423295 | 0.76 | LMNA (0.42) | CNR2NPC1POLBSMN1; SMN2SMYD3 | |
| SCHEMBL31422776 | 0.76 | LMNA (0.42) | CNR2NPC1POLBSMN1; SMN2SMYD3 | |
| SCHEMBL31422872 | 0.75 | CNR2 (0.46) | CNR2 | |
| SCHEMBL31423163 | 0.73 | NOTUM (0.43) | CNR2POLBKDM4EALDH1A1GAA | |
| SCHEMBL31422779 | 0.73 | CNR2 (0.42) | CNR2POLBKDM4EALDH1A1GAA | |
| SCHEMBL31422800 | 0.72 | CNR2 (0.36) | CNR2POLBKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |