Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423174 | 0.83 | LMNA (0.49) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL31423247 | 0.78 | CNR2 (0.40) | KDM4EALDH1A1GAAHPGDCAMKK1 | |
| SCHEMBL31423086 | 0.77 | CNR2 (0.39) | KDM4EALDH1A1GAAHPGDCAMKK1 | |
| SCHEMBL31422779 | 0.76 | CNR2 (0.42) | PKMKDM4EALDH1A1GAAHPGD | |
| SCHEMBL31423273 | 0.76 | CNR2 (0.43) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL31423108 | 0.74 | SMYD3 (0.42) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL31422972 | 0.73 | CAMKK2 (0.43) | MAPTTDP1KDM4ENPC1RAB9A | |
| SCHEMBL31423010 | 0.73 | CAMKK2 (0.43) | MAPTTDP1KDM4ENPC1RAB9A | |
| SCHEMBL31423163 | 0.72 | NOTUM (0.43) | KDM4EALDH1A1GAAHPGD | |
| SCHEMBL31422872 | 0.71 | CNR2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |