SCHEMBL31423938

SCHEMBL31423938

Nc1cc(F)c(I)c(F)n1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CGAS Q8N884 1/20 0.30
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30
MAPT P10636 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24103866 0.77 ADORA2B (0.34)
SCHEMBL24103030 0.75
SCHEMBL30930521 0.75 ALDH1A1 (0.38) NOS3NOS1NOS2MAPTTDP1
SCHEMBL23134770 0.71 NOS2 (0.39) NOS3NOS1NOS2
SCHEMBL23147899 0.68 NOS3 (0.32) NOS3NOS1NOS2
SCHEMBL29722086 0.68 NOS3 (0.32) NOS3NOS1NOS2
SCHEMBL24124153 0.67
SCHEMBL2360976 0.66 ALDH1A1 (0.33) CGASMAPT
SCHEMBL25198744 0.65
SCHEMBL28029050 0.65 REV1 (0.40) NOS3NOS1NOS2MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025054386-A1 CDK2 INHIBITORS AND USES THEREOF ODYSSEY THERAPEUTICS, INC. (US) 2025-03-13 WO disclosed